Recovery of patients from pediatric inflammatory multisystem syndrome (PIMS) and the impact of this disease on exercise tolerance

Background
Pediatric inflammatory multisystem syndrome (PIMS) is a rare but serious condition that typically manifests in children as a complication 2-4 weeks after they have been infected with the coronavirus disease 2019 (COVID-19). It is characterized by a wide range of symptoms, including high fever, inflammation of multiple organs, and potentially life-threatening complications. Early recognition and prompt medical intervention are crucial in managing PIMS and minimizing its impact on children's health.

Aims
This study aimed to evaluate the performance of patients six months after undergoing PIMS and the impact of the disease on physical activity and functioning

Material and methods
52 children aged 0-17 years were included in the study. They were divided into two groups: study (B) and control (K). 13 patients in group B and 16 in group K took part in a fitness test with the 6-minute walk test (6MWT). Total of 30 patients were surveyed in the PIMS questionnaire. Medical records of 36 people with PIMS syndrome were also included.

Results
Patients from both groups in the 6MWT achieved results that were not abnormal, and no differences between them were observed. In the physical activity undertaken before and after PIMS syndrome, no differences were observed. The patients' health status improved six months after the disease. PIMS syndrome affected the deterioration of general health, increased fatigue, and the occurrence of headaches and sleep disorders but did not affect the desire for social interaction.

Conclusions
Exercise tolerance in children after PIMS syndrome does not differ from the norm. Having PIMS syndrome does not affect the physical activity undertaken by children. The patients' health status improved 6 months after hospitalization. Survival of PIMS syndrome affected fatigue, headaches, and sleep disorders but did not affect the desire to interact with peers.